At Adaptive, we’re Powering the Age of Immune Medicine. Our goal is to harness the power of the adaptive immune system to transform the way diseases are diagnosed and treated.

As an Adapter, you’ll have the opportunity to make a difference in people’s lives. With Adaptive, you’ll create a career highlight through collaboration with bright, curious colleagues working at the apex of innovation and application.

It’s time for your next chapter. Discover your story with Adaptive.

Position Overview

Join us to build the future of immune medicine. As a Senior Software Engineer at Adaptive Biotechnologies, you’ll craft and maintain software systems that drive cutting-edge research, partnering closely with engineering, researchers, and customer-facing teams to turn complex requirements into scalable, high-impact platforms. Your work will accelerate breakthroughs in computational biology and machine learning by shaping our platform for speed, clarity, and discoverability - fueling faster product development and commercialization. We’re looking for a versatile engineer who thrives at the intersection of research and production; combining strong software fundamentals with experience in distributed systems or cloud infrastructure, fluency in data-intensive workflows, and a passion for innovation balanced with compliance, observability, and operational excellence.

Key Responsibilities and Essential Functions

Responsible for all phases of software development including specification, design, implementation, test, deployment of software that supports Adaptive’s software systems.
Assists in troubleshooting and resolving system issues
Collaborates with software engineering colleagues and stakeholders to develop solutions for both current and future business needs

Position Requirements

Required

Bachelor’s degree in Computer Science or certified Bootcamp and/or 10+ years of relevant experience or Master’s degree with 7+ years of relevant experience
Familiarity with standard software development best practices: source code control, unit testing, in-code documentation and automated build environments
Superior communication skills in a highly diverse cross-discipline environment
Extensive experience with Python
Experience managing cloud resources and/or Kubernetes environments
Experience with managing and scaling large datasets and compute-intensive workflows (e.g. Spark-based applications or distributed machine learning)
Experience with SQL relational databases
Ability to work in Linux environment

Preferred

Experience developing MLOps solutions to support high-velocity research
Experience designing and building DevOps tooling to support software and research teams (e.g. CI/CD pipelines)
Experience using Infrastructure as Code to deploy resources (preferably Pulumi)
Experience with Azure cloud resources
Experience with a strongly typed object-oriented language (preferably Java or C#)
Familiarity with developing front-end applications (React + TypeScript) and REST APIs

Working Conditions

Primarily work in an office environment and work from home.
Regular weekday work hours, with occasional weekend/after-hours planned or unplanned work as needed.
Some travel for team building events and project related work.

Physical Requirements

If working on Automation team:

Physically able to lift 50 pounds
Ability to stand or walk for much of the day.

#LI-Remote

Compensation

Salary Range: $132,000 - $198,000

Other compensation elements include:

equity grant
bonus eligible

ALERT: Malicious groups posing as Adaptive employees have recently used fraudulent email aliases to extend employment offers, provide fake documents, and request sensitive personal and financial information. Legitimate Adaptive employment opportunities are initiated through our careers page and extended after multiple interviews with verified employees. Adaptive does not ask new hires to purchase anything out-of-pocket, including home office supplies and equipment.

Interested in this position, but don’t meet all the requirements? Adaptive is committed to building diverse, equitable, and inclusive teams across our organization. Please consider applying even if your experience doesn’t match all the qualifications; you may be the exact candidate we’re searching for!

Adaptive is not currently sponsoring candidates requiring work authorization support for this position.

Adaptive’s posted compensation information includes a base salary (or hourly rate) range and summary of other available total compensation. The base salary range represents a minimum-to-maximum salary (or hourly rate) available to candidates upon extension of offer. Base salary is thoughtfully considered upon offer and is determined through multiple evaluation checks throughout the interview process, including: a candidate’s ability to meet minimum qualifications (skills/experience/education), a candidate’s ability to thoughtfully address preferred qualifications, current market conditions, and internal pay equity. Listed base salary is exclusive of bonus, commission, equity, differential pay, benefits, and other incentives.

Adaptive's benefits at-a-glance.

Adaptive Biotechnologies is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against based on disability. Please refer the “Know Your Rights: Workplace Discrimination is Illegal” Poster for more information. If you’d like to view a copy of the company’s affirmative action plan or policy statement, please email [email protected].

If you have a disability and you believe you need a reasonable accommodation to search for a job opening or to submit an online application, please e-mail [email protected]. This email is created exclusively to assist disabled job seekers whose disability prevents them from being able to apply online. Only messages left for this purpose will be returned. Messages left for other purposes, such as following up on an application or technical issues not related to a disability, will not receive a response.

NOTE TO EMPLOYMENT AGENCIES: Adaptive Biotechnologies values our relationships with our Recruitment Partners and will only accept resumes from those partners who have active agreements with Adaptive. Adaptive Biotechnologies is not responsible for any fees related to resumes that are unsolicited or are received by any employee of Adaptive Biotechnologies who is not a member of the Human Resources team.

Senior Software Engineer

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