Senior Director, Marketing Excellence

The Opportunity

The Senior Director, Marketing Excellence, will play a pivotal role in shaping Amylyx’s commercial strategy and driving seamless, integrated engagement across all customer touchpoints. This leader will be responsible for designing and executing a comprehensive, enterprise-wide omnichannel vision that connects with healthcare professionals and community members (patients and caregivers) through personalized, high-impact experiences. This role will integrate digital and traditional channels, leverage data-driven insights, and collaborate across functions to ensure alignment with brand objectives and launch plans. As a key strategic leader, you will shape how Amylyx engages customers, driving innovation and measurable impact. This role will also lead Marketing Operations with a focus on excellence across all aspects of Marketing.

This is a unique opportunity for a strategic, forward-thinking marketer to define how Amylyx leverages technology, analytics, and creative storytelling to deliver consistent, high-value engagement. By combining strategic insight with flawless execution, this individual will help position Amylyx as a leader in omnichannel excellence within the life sciences industry.

Responsibilities

• Lead the enterprise-wide digital and omnichannel vision for Amylyx, establishing the standards, principles, and operating model that guide customer engagement across all channels.
• Develop and execute an integrated omnichannel marketing capability and strategy aligned with brand objectives and launch timelines, supported by a robust digital customer engagement capability roadmap.
• Define and optimize end-to-end customer journeys for HCPs and community members to ensure personalized, consistent experiences across personal and nonpersonal touchpoints, overseeing campaign execution across CRM, marketing automation platforms, and third-party media.
• Partner with brand teams to advise on the creation of compelling, compliant, audience-appropriate content while ensuring alignment with regulatory requirements.
• Collaborate cross functionally with Commercial, Medical Affairs, and Corporate Communications to ensure seamless integration and synergy across all customer-facing activities.
• Establish measurement frameworks with KPIs and dashboards to monitor engagement, conversion, and ROI, partnering closely with IT and analytics teams to ensure the data infrastructure supports real-time optimization.
• Drive continuous improvement by leveraging data driven insights to evolve strategy, enhance performance, and identify new opportunities for customer impact.
• Oversee governance, optimization, and administration of marketing CRM, marketing automation, analytics platforms, asset management systems, and related martech tools.
• Oversee congress operations, material distribution, inventory, print/fulfillment, and speaker bureau operations and related budgets.
• Develop procedures, documentation, and training to ensure compliant, efficient, and repeatable execution across Marketing.

Requirements

• Bachelor’s degree, MBA or advanced degree preferred
• 10+ years of marketing experience, with at least 5 years in omnichannel or digital marketing leadership roles within biotech/pharma
• Proven track record of developing and executing integrated marketing strategies for product launches
• Deep understanding of regulatory and compliance requirements in the life sciences industry
• Strong analytical skills and experience with marketing technology platforms (CRM, automation, analytics)
• Exceptional leadership, communication, and project management skills

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations candidates must be able to attend meetings at our office in Cambridge, MA on a regular basis.  Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis.
• When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.