About Apogee Therapeutics

Founded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. At Apogee, you can actively contribute to shaping the company culture, take on various roles and responsibilities, and grow professionally.

Apogee Therapeutics is a clinical-stage biotechnology company advancing novel biologics with potential for differentiated efficacy and dosing in the largest I&I markets, Apogee’s antibody programs are designed to overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. Zumilokibart (APG777), the company’s most advanced program, is being initially developed for the treatment of atopic dermatitis (AD), which is the largest and one of the least penetrated I&I markets, as well as asthma. With four validated targets in its portfolio, Apogee is seeking to achieve best-in-class efficacy and dosing through monotherapies and combinations of its novel antibodies. Based on a broad pipeline and depth of leadership and expertise, the company believes it can deliver value and meaningful benefit to patients underserved by today’s standard of care.

We are a fast-paced company committed to building an exceptional culture, founded on our C.O.R.E. values: Caring, Original, Resilient and Egoless and a commitment to refusing to stop at “good enough”.

If this sounds like you, keep reading!

Role Summary

The Senior Director, Commercial Strategy will serve as a strategic commercial leader for a growing clinical‑stage biotechnology company with a diversified pipeline, including a lead asset in Atopic Dermatitis entering phase 3 clinical trials within the next 12 months and two additional programs in earlier clinical stage development. This role is responsible for supporting the ongoing planning and execution of the Company’s five-year U.S. commercial roadmap across a variety of initiatives, workstreams and projects. The Senior Director will work closely with Clinical, Medical Affairs, Business Development & Strategy, Regulatory, Finance, and Executive Leadership to ensure commercial perspectives are integrated early and effectively throughout the development programs. In addition, the role will be responsible for building and executing a Commercial competitive intelligence process to keep up to date on the competitive market dynamics and developments across our prioritized therapeutic areas. The Sr Director, Commercial Strategy will report directly to the SVP, Commercial Strategy & Operations.

Key Responsibilities

Work closely with Commercial Leadership Team in the development of a comprehensive commercial strategy and pre-launch plan for the Company’s lead asset in moderate-to-severe Atopic Dermatitis
Oversee and maintain the execution of the 5-year U.S. commercialization roadmap across Operations, Marketing, Market Access and Sales through cross functional commercial projects and initiatives that will define the go-to-market strategy
Partner with Commercial Leadership in the evaluation, assessment and implementation of commercial operating model which includes commercial processes, systems and capabilities as well as the organizational design & structure to support commercialization
Partner closely with Marketing & Market Access organizations to understand the needs and operational support required by each organization pre and post launch and lead efforts to incorporate those into go-to-market planning
Serve as a member of cross functional program team workstreams across various portfolio development programs to ensure Commercial perspective is accounted for in the plans of Clinical Development, Medical Affairs, and Regulatory functions
Establish a market and commercial competitive intelligence process to help the organization stay up to date on the latest market changes and competitive dynamics that will shape asset positioning and target product profiles (TPPs)

Ideal Candidate

Bachelor’s degree required; advanced degree (MD, PhD, or other relevant graduate degree) preferred, particularly for candidates with management consulting or strategic advisory experience
Approximately 10+ years of industry experience, including 5+ years of strategic consulting experience or strategy experience at a pharmaceutical or biotech company
Broad experience across relevant commercial roles and functions, including at least one role with primary responsibility for commercial strategy development and execution
Proven track record of shaping and executing effective commercial strategies in rapidly evolving biotech organizations, resulting in meaningful commercial impact
Excellent verbal and written communication skills
Advanced skills in Excel and PowerPoint, including the ability to build clear, data‑driven analyses and create executive‑ready presentation decks
Ability to thrive in a remote work environment by engaging actively and building rapport with colleagues through virtual meetings and collaboration tools
Successfully exhibit Apogee’s C.O.R.E. values: Caring, Original, Resilient and Egoless
Position requires up to 20% travel including mandatory in-person attendance at All Hands meeting, typically held twice per year

The anticipated salary range for candidates for this role will be $255,000- $285,000. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography.

What We Offer

A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
Commitment to growing you professionally and providing access to resources to further your development
Apogee offers regular all team, in-person meetings to build relationships and problem solve

E-Verify Participation: As part of the I9 verification of authorization to work in the US, Apogee participates in E-Verify. To learn more about E-Verify please review this poster.

Apogee Therapeutics is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

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It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Senior Director, Commercial Strategy

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