Scientist (PhD) Protein Sciences

Ascendis Pharma is seeking a highly motivated Associate Scientist (M.Sc.) or Scientist (Ph.D.) to join the Protein Sciences group. In this role, you will be responsible for producing therapeutic protein candidates for pre-clinical in vitro and in vivo testing. We are looking for a creative and proactive scientist with strong problem-solving skills, a can-do attitude, and demonstrated expertise in protein sciences, including expression, purification, and characterization.

Do you thrive in a collaborative team where supporting others, sharing knowledge, and clear communication are part of everyday work?  Are you excited to apply scientific creativity - developing new ideas, technologies, or approaches - while working on a solid foundation of analytical thinking and rigor? Do you enjoy working on challenging projects and adapt easily to changing priorities and evolving goals? Would you like to apply your scientific expertise to help develop novel drugs that improve patients' lives?

Beyond technical excellence, we are looking for a colleague who brings curiosity and conceptual thinking to the table - to contribute to the generation of new ideas and innovative concepts.

Your Responsibilities:

• Develop and optimize protein production processes (molecular cloning, expression, purification) for therapeutic candidates
• Characterize protein quality (purity, yield, stability, activity)
• Continuously improve existing workflows and implement new technologies
• Analyze, document, and present results to multidisciplinary project teams
• Communication with vendors and CROs, and CDMOs
• Prepare SOPs, scientific reports, patent examples, and conduct literature research

Requirements

• Master’s degree (Associate Scientist) or Ph.D. (Scientist) in biochemistry, biotechnology, or a related field
• Strong hands-on experience in protein purification and analytical techniques (ÄKTA/HPLC); deep knowledge of chromatography and downstream process development
• Proficiency in protein characterization (e.g., SEC, RP-HPLC)
• Experience in mammalian protein expression systems (e.g., HEK293, CHO); skills in molecular biology and protein engineering are highly desired
• High motivation and flexibility to support therapeutic protein development
• Structured, detail-oriented working style
• Excellent communication skills in English; good working knowledge of German
• Strong team player with a passion for interdisciplinary collaboration and innovation

Benefits

• Onboarding:
  A structured Onboarding program designed to help you settle in quickly and get familiar with your role and our company culture

• Learning & Development:
  Customized training opportunities with generous financial support to foster your professional growth
• Connectivity & Mobility:
  Direct access to a tram station and parking spaces for both cars and bicycles
  We offer a JobTicket based on the Deutschlandticket, and after your probation period, you’ll have the option to lease a JobRad (company bike)
• Food & More:
  Enjoy free soft drinks, fresh fruit, a wide variety of snacks, and a complimentary lunch every day
• Compensation & Benefits:
  An attractive salary package including a company pension plan (bAV), internet allowance, and both short- and long-term incentive programs
• Modern Work Environment:
  Your new workspace comes equipped with a brand-new laptop and an iPhone

If you want to be part of our team, we offer you an exciting and challenging full-time position with attractive benefits in an international company. Send your comprehensive application out now!