The Manager of End User Compute Services is a collaborative leader and go-getter responsible for the global strategy and optimization of the Microsoft 365 ecosystem (O365, Intune, Entra ID), Mac management (Jamf), and VDI environments. This role requires a high-energy individual who blends deep technical execution with people management to deliver a secure, automated, and seamless digital workplace. You will work hand-in-hand with SecOps, HR and BRM to drive zero-touch automation across the entire employee lifecycle.
Main Duties & Responsibilities
• Collaborative Leadership: Lead and mentor a global team of engineers to deliver high-performing identity and endpoint services.
• M365 Mastery: Administer and optimize the Microsoft 365 tenant, including Exchange Online, SharePoint, OneDrive, Teams, and associated collaboration tools.
• Security Partnership: Work closely with SecOps to implement Zero Trust principles, Conditional Access, and Defender integration.
• Automation & Lifecycle: Design and deploy end-to-end employee lifecycle automations integrated with HRIS systems (Workday, etc) to ensure seamless onboarding/offboarding.
• Unified Endpoint Management: Oversee operations for Intune and Microsoft Configuration Manager (MECM) while providing expert-level management of Apple Mac environments via Jamf.
• VDI Management: Lead the strategy and delivery of virtual desktop solutions (Azure Virtual Desktop/Windows 365) to support a global, flexible workforce.
• Governance: Drive license optimization, patch compliance, and consistent hardware/software configurations across Windows and macOS.
• Operational Excellence: Define and track KPIs/SLAs while acting as a high-level technical escalation point for complex incidents and ensure root-cause resolution for recurring issues.
• Develop technical documentation, SOPs, and training programs for IT staff and end-users.
• Perform other duties as assigned by leadership.
Education and Experience
Minimum Education & Experience:
• Bachelor’s degree in computer science, Information Systems, or related field.
• 10+ years of IT experience with at least 5 years managing M365, Intune, and identity platforms in an enterprise setting.
• Proven track record leading teams, managing budgets, and implementing enterprise workplace solutions.
Knowledge, Skills, and Competencies
• Microsoft Expert: Deep technical mastery of M365, Entra ID (hybrid identity, SSO & MFA), Intune, Defender Suite, and Autopilot.
• Enterprise Management Tools: Proven experience with Microsoft Configuration Manager (MECM) and co-management strategies.
• Apple Specialist: Proven experience managing macOS and iOS in an enterprise setting using Jamf Pro and Apple Business Manager.
• VDI Mastery: Technical proficiency in Windows and VDI platforms to support diverse user needs.
• Automation Mindset: Expert-level PowerShell scripting and experience with API-based integrations (Graph API) for HRIS/ITSM workflows.
• Collaboration & Communication: Exceptional ability to partner across departments (Security, BRM, PMO, HR) and translate technical complexity into business value.
• Regulatory Knowledge: Familiarity with maintaining compliance for SOC2, HIPAA, or ISO27001 standards
• Experience implementing and governing enterprise collaboration tools (Teams, SharePoint, OneDrive).
• Excellent analytical, financial, and decision-making skills—able to link technology investment to business outcomes.
• Working knowledge of ITIL and Enterprise IT Operations concepts.
• Highly organized, with a focus on accountability, service quality, and continuous learning.
Preferred Education & Experience (optional):
• Microsoft Certified: Enterprise Administrator Expert or Jamf Certified Admin (preferred).
• Experience with ITSM frameworks (ITIL) and service delivery in regulated industries.
Or equivalent combination of education, professional training and experience that provides the individual with the required knowledge, skills, and abilities to perform the job.
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Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.
If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at [email protected].
It has come to our attention that some individuals or organizations are reaching out to job seekers and posing as potential employers presenting enticing employment offers. We want to emphasize that these offers are not associated with our company and may be fraudulent in nature. Please note that our organization will not extend a job offer without prior communication with our recruiting team, hiring managers and a formal interview process.
Precision Medicine Group leverages specialized expertise in precision medicine to help pharma & life sciences clients innovate, develop, and commercialize next-generation medical products. By applying relevant insights and specialized capabilities, the...
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