About SpringWorks Therapeutics:

SpringWorks Therapeutics, a healthcare company of Merck KGaA, Darmstadt, Germany, is a commercial-stage biopharmaceutical company dedicated to improving the lives of patients with rare tumors.

We developed and are commercializing the first and only FDA and EC approved medicine for adults with desmoid tumors and the first and only FDA and EC approved medicine for both adults and children with neurofibromatosis type 1 associated plexiform neurofibromas (NF1-PN).

At SpringWorks, we are committed to finding answers people with rare tumors need. We thrive in an atmosphere of passion and tenacity, fueled by the excitement of the possibilities science may unlock and driven to work with urgency because of the importance of our work. We value authenticity because diverse backgrounds, cultures, styles and abilities can only help us find the answers that people with rare tumors are looking for.

Your Role:

The Head of North America Medical Affairs is a senior executive leader responsible for shaping and executing the medical vision and strategy across the U.S. and Canada. This role requires a very strong and dynamic leader, able to oversee two distinct medical affairs teams: SpringWorks North America Medical Affairs and EMD Serono Medical Affairs, each operating as separate, high-functioning groups. Both teams will report into the Head of North America Medical Affairs (who will report into the Head of Worldwide Medical Affairs, Rare Tumor) and are aligned under a unified leadership to ensure scientific excellence, regulatory compliance, and strategic impact across the Merck KGaA Darmstadt Germany Healthcare business in the North America region.

This leader will be accountable for a broad and complex team of medical professionals focused on the North America region across SpringWorks and EMD Serono. The scope of responsibility will be different for both entities but will include Field Medical Teams, Medical Outcome Liaison team (as exists for EMD Serono), within market medical operations, within market HEOR, Strategic Medical Programs, and therapeutic area leadership in Oncology, Neurology & Immunology, and Reproductive Health & Endocrinology for EMD Serono and Rare Tumors leadership for SpringWorks.

This leader will be a key member of the Worldwide Medical Affairs Leadership Team for SpringWorks, and the U.S. Commercial Leadership Team for EMD Serono. This role will be pivotal in aligning medical strategy with business objectives and driving innovation across the product lifecycle—from early development through post-marketing.

The ideal candidate is a visionary and collaborative leader with deep scientific expertise, strong business acumen, and the ability to influence across global and regional stakeholders. This role requires a passion for advancing patient care through science, a commitment to operational excellence, and the ability to lead through complexity in a dynamic, fast-paced environment.

Location Classification – Hybrid:

This role will be required to work onsite 2 days a week (Tuesday and Wednesday), or more depending on business needs. #LI-Hybrid

Essential Duties and Responsibilities:

Develop and ensure execution of a clear set of medical affairs strategies for the U.S. and Canada, aligned with business and brand objectives.
Lead the teams to shape and adapt global strategies to address the in-market needs for North America, ensuring customer needs are met.
Provide Medical leadership across various North America functional partners such as Commercial, Pharmacovigilance, Compliance, Regulatory etc., to drive in market product strategy including product and disease positioning, as well as tactical execution of projects.
Define and lead disease awareness initiatives, publication planning, advisory boards, and investigator-sponsored research (IITs).
Drive post-marketing strategy and provide strategic input into late-stage clinical development.
Represent the company in different fora as needed, such as industry fora, patient advocacy fora, scientific and clinical expert groups that are relevant to our business, ensuring SpringWorks’ and EMD Serono’s medical voice is heard.
Facilitate cross-functional alignment with R&D, Commercial, and Global Medical Affairs to support pipeline and lifecycle success for both SpringWorks and EMD Serono products.
Lead and further develop two high-performing medical affairs teams (SpringWorks North America and EMD Serono), ensuring clear structure, accountability, and collaboration.
Set strategic objectives, manage performance, coach talent, and ensure effective resource allocation and budget management.
Ensure launch readiness and contribute to global and regional medical and publication plans.
Apply situational leadership to foster a culture of innovation, agility, and excellence.
Establish and maintain strong relationships with key opinion leaders (KOLs), healthcare professionals, and advocacy groups at national and international levels.
Perform other duties and responsibilities assigned.

Role Requirements:

Education: Doctor of Medicine (MD required)
15+ years of progressive experience in Medical Affairs or related functions, including global and regional roles
7+ years of people leadership, including 3+ years managing multiple functions or teams
Demonstrated track record of taking products from late-stage development through launch and lifecycle management
Proven success in designing and executing medical affairs strategies, including post-approval clinical protocols
Experience in developing and leading medical teams in dynamic, competitive environments
Deep understanding of health economics, outcomes research, and health technology assessment
Strong experience in building and managing KOL networks nationally and internationally
Proven ability to lead large teams and develop leaders of leaders
Experience working within a project-based organization and deep familiarity with SOPs and regulatory frameworks (FDA, PhRMA, OIG, etc.)
Demonstrated success in external partnerships and cross-functional collaboration
Knowledge of clinical research methodology and Good Clinical Practice (GCP) preferred
Sophisticated understanding of North America regulatory, medical, and economic environments
Strong knowledge in real-world evidence generation, medical information, and commercialization support
Strong knowledge of business planning, data analysis, and budget management
Expert-level understanding of the commercial, clinical, and regulatory aspects of the pharmaceutical industry
Ability to translate complex scientific concepts into actionable strategies
Willingness and ability to travel domestically and internationally as required
Model SpringWorks Leadership Principles to drive a collaborative function that embraces innovation and drives superior employee experience through growth management.
Embody the SpringWorks Values to act with empathy and humility to drive a culture that takes ownership and accountability for their individual and teams’ performance.
Strong interpersonal communication skills to collaborate with colleagues, stakeholders, and vendors effectively and clearly in a remote hybrid work environment.

SpringWorks Leadership Principles:

Change Steward - Recognize that change is essential; set goals that align to the Company’s strategy and create positive momentum for change; adapt business practices as necessary to adjust to ever changing requirements
Excellence Driver - Drive high performance and ownership through an open dialog; recognize performance, empower teams and create accountability for results
Growth Coach - Set clear expectations, provide frequent feedback, coaching, and encourage continuous learning; leverage individual strengths to help SpringWorkers unleash their potential and grow in their jobs and careers
Community Builder - Establish connections with others to build strong teams that trust each other and are great at collaborating to achieve goals; create a diverse, inclusive, and psychologically safe environment

Compensation & Benefits:

The expected salary range for this position is $450,000.00 – $500,000.00. Actual pay will be determined based on experience, qualifications, location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

We offer best-in-class benefits for our team of SpringWorkers who work with urgency on behalf of patients suffering from devastating diseases. Interested in learning more, review additional information here Benefits.

EEO Statement:
SpringWorks maintains an EEO Policy providing for equitable opportunities for employment and conditions of employment to all employees and applicants regardless of actual or perceived sex (including pregnancy, childbirth, breastfeeding or related medical conditions), gender, gender identity or gender expression, sexual orientation, partnership status, marital status, familial status, pregnancy status, race, color, national origin, ancestry, caste, religion, religious creed, age, alienage or citizenship status, veteran status, military status, physical or mental disability, past or present history of mental disorder, medical condition, AIDS/HIV status, sickle cell or hemoglobin C trait, genetic predisposition, genetic information, protected medical leaves, victims of domestic violence, stalking, or sex offense, political affiliation and any and all other characteristics or categories protected by applicable federal, state or local laws. SpringWorks treats all employees and applicants fairly in the selection process (and in other personnel activities) by giving all employees and applicants the same opportunities for employment. SpringWorks’ Equal Employment Opportunity Policy is intended to ensure that there are no barriers that would prevent members of a protected group from a fair and equitable opportunity to be hired, promoted, or to otherwise take advantage of employment opportunities.

This Equal Employment Opportunity Policy applies to all aspects of employment, including, without limitation, recruitment, hiring, placement, job assignment, promotion, termination, transfer, leaves of absence, compensation, discipline, and access to benefits and training. Any violation of this Policy will result in disciplinary action up to and including termination of employment.

Privacy:
Upon submission of this form I understand that SpringWorks Therapeutics is based in the United States and personal data submitted in the form will be transferred and accessed in the U.S.. Information about SpringWorks Therapeutics’ privacy practices can be found at Privacy Policy - Springworks (springworkstx.com).

Head of Medical Affairs, North America

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