Director, Clinical Operations

TLDR

Lead the operational strategy for a global oncology program, ensuring high-quality, timely execution across regions and enhancing compliance with regulatory standards.

What’s in it for you?

Frontier Medicines is seeking a Director, Clinical Operations Program Lead to drive the operational strategy and execution of a global oncology program as it advances through clinical development. This role will serve as the operational leader for the program, translating clinical and business strategy into high-quality, on-time study delivery across regions and partners.

Working in close partnership with cross-functional leaders and global CROs, the Director will oversee program-level planning, risk mitigation, vendor management, and budget accountability while ensuring compliance with global regulatory standards. The ideal candidate brings deep oncology experience, strong global study oversight, and the ability to influence stakeholders, anticipate challenges, and deliver results in a dynamic biotech environment.

Requirements

What will you be doing?

• Develop clinical operational strategy and ensure clinical research studies are executed with quality and efficiency, on-time, within budget, and to meet company objectives

• Translate program strategy into operational execution by developing the clinical operations plan (or strategy) and connecting science with the business, operations, and patients

• Identify and evaluate risks and mitigations at program level to achieve the program strategy.

• Interact with and influence management and cross-functional team members to achieve program objectives and represent Clinical Operations at cross-functional meetings

• Review and provide clinical operations content to clinical and regulatory documents

• Manage overall external budget management

• Execute clinical programs in compliance with quality standards (ICH/GCP, Global Regulations, and company policies and procedures)

• Drive activities and find solutions to deliver on the program

Traits we believe make a strong candidate:

• Bachelor’s degree or work experience equivalent is required, preferably in a scientific field.

• 10+ years of Biotech/Pharma clinical research related experience

• Strong vendor management and oversight experience

• Strong experience in oncology

• Proven ability in working on a global team in the management and completion of multiple, complex clinical studies

• Competent in application of standard business procedures (SOPs, ICH, Global Regulations, Ethics and Compliance)

• Integral participation in initiatives or advancement strategies for clinical operations

• Experience in successful study initiation through study completion and in multiple phases of studies (Phases 1-3)

• Strong communication and stakeholder management skills.

• Legally authorized to work in the United States.

Benefits

  • Health Care Plan (Medical, Dental & Vision)
  • Retirement Plan (401k, IRA)
  • Life Insurance (Basic, Voluntary & AD&D)
  • Paid Time Off (Vacation, Sick & Public Holidays)
  • Family Leave (Maternity, Paternity)
  • Short Term & Long Term Disability
  • Training & Development
  • Free Food & Snacks
  • Wellness Resources
  • Stock Option Plan

At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $195,000 - $245,000. Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.

This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.

Benefits

Equity Compensation

Stock Option Plan

Health Insurance

Health Care Plan (Medical, Dental & Vision)

Learning Budget

Training & Development

Other Benefit

Wellness Resources

Paid Parental Leave

Family Leave (Maternity, Paternity)

Paid Time Off

Paid Time Off (Vacation, Sick & Public Holidays)

Frontier Medicines is a pre-clinical stage biopharmaceutical company that is pioneering breakthrough technologies to drug the “undruggable” proteome. Frontier Medicines’ proprietary platform uses chemoproteomics – an innovative approach to chemically interrogate proteins in living systems – to discover and pharmacologically target new binding pockets (or hotspots) on proteins for the purpose of making them accessible to therapeutic intervention. Our therapeutic programs are focused on some of the most important and difficult targets in human disease, starting with cancer, in order to change the lives of patients for the better. As a Fierce 15 company FierceBiotech recognized Frontier as one of the most promising private biotechnology companies in the industry.

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Salary
$195,000 – $245,000 per year
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