CoOp, Computational Biology

AI overview

Join a dynamic team to analyze Drug-seq data, delivering insights to guide compound selection and integrate results with AI models.

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. 


 

About the role

Join our Functional Genomics team to analyze Drug-seq data from high-throughput chemical and CRISPR perturbation screens that drive mechanism-of-action studies and can be used to train AI models . You’ll design and run scalable analyses across thousands of perturbation and cell type combinations, turning raw Drug-seq readouts into robust, reproducible insights. Day to day, you’ll integrate high-throughput results with pathway/ontology annotations, and deliver crisp summaries and figures to wet-lab partners and program teams.This role suits someone eager to apply data science computational biology to high-throughput datasets, delivering analyses that shape compound selection and spark testable hypotheses.

What you’ll do

  • Process and analyze Drug-seq transcriptomic datasets from chemical libraries and CRISPR perturbation screens across multiple cell types.
  • Perform rigorous QC, normalization, and differential expression (DESeq2/edgeR); aggregate and compare signatures across conditions.
  • Build reproducible pipelines (Snakemake/Nextflow; R/Python) and clean analysis notebooks (R Markdown/Jupyter).
  • Annotate results with pathways/ontologies (GSEA/fgsea, Enrichr) and public references; generate publication-quality visualizations.
  • Collaborate with wet-lab scientists to plan screens, define controls/replicates, and translate findings into actionable follow-ups.
  • Contribute curated features/labels that help train and evaluate AI/ML models for MoA/target inference and compound ranking.
  • Document methods and results; share concise updates with stakeholders.

The base salary range for this role is $25 hourly. Actual pay within this range will depend on a candidate's skills, expertise, and experience. We also offer company stock awards, a comprehensive benefits package including medical, dental & vision coverage, health spending accounts, voluntary benefits, leave of absence policies, 401(k) program with employer contribution, 8 paid holidays in addition to a full-week winter shutdown and unlimited Paid Time Off policy.

Ginkgo has implemented a return to office policy effective October 1, 2025 with required in-office days: Tuesday, Wednesday, Thursday.  This policy applies to all employees who live within 50 miles of Ginkgo’s offices in Boston, MA, Emeryville, CA and West Sacramento, CA. **Biosecurity positions are excluded from this policy. 

 
It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees, employment applicants, and EOE disability/vet. 
 

 
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Perks & Benefits Extracted with AI

  • Health Insurance: comprehensive benefits package including medical, dental & vision coverage
  • Full-week winter shutdown: full-week winter shutdown
  • Paid Time Off: unlimited Paid Time Off policy

Important Notices: If you have a disability and you wish to discuss potential accommodations related to applying for employment, please contact [email protected].   Recruitment & Staffing AgenciesGinkgo Bioworks does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Ginkgo or its employees is strictly prohibited unless contacted directly by Ginkgo’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Ginkgo Bioworks, and will not owe any referral or other fees with respect thereto.   Scam AlertPlease be aware of the potential for scams from individuals, organizations and internet sites that claim to represent Ginkgo Bioworks, Inc. in recruitment activities. Ginkgo conducts a formal recruitment process for all authorized positions posted and does not conduct interviews via social media or other third-party sites. This site is secure and any applications made here will feed to our legitimate Applicant Tracking System. If you’re contacted by a Ginkgo Recruiter, please ensure whomever is contacting you truly represents Ginkgo. We will never ask for the exchange of any money or credit card details during the recruitment process. Please be aware of any suspicious email activity from people who could be pretending to be recruiters or senior professionals at Ginkgo and please report any suspicious recruiting activity to: Your state’s Attorney General’s OfficeInternet Crime Complaint CenterUSA.govBetter Business Bureau     

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