Clinical Research Manager

Union: Non-Union 
Number of Vacancies: 1
Site: Princess Margaret Cancer Centre
Reports to: Principal Investigator
Hours: 37.5 hours per week
Shifts: Monday-Friday
Status: Permanent Full-Time
Closing Date: December 29, 2025

Position Summary:
The Clinical Research Manager will play a pivotal leadership role within the newly established Peter Gilgan Centre for Early Cancer Detection Research at Princess Margaret Cancer Centre, supporting one of the most ambitious early cancer detection research initiatives globally. This transformative program brings together world-leading scientists, clinicians, and data scientists to develop and validate technologies for early cancer detection and molecular residual disease (MRD) monitoring, with the ultimate goal of improving patient outcomes through earlier diagnosis and intervention.

Reporting to Principal Investigator(s), the Clinical Research Manager will be responsible for the end-to-end operational management of a diverse portfolio of clinical and translational research studies. The role requires close collaboration with investigators across disease sites, other program managers, laboratory teams, industry partners, and institutional stakeholders to ensure seamless integration of clinical and discovery research. The successful candidate will provide strategic and hands-on leadership to a growing team of clinical research professionals, ensuring resourcing, training, performance oversight, and continuous process improvement as the program rapidly expands. 

This is a highly visible leadership role offering a unique opportunity to help build and shape a globally significant research program at the intersection of innovation, clinical care, and translational science—directly impacting how cancer is detected and treated in the future.

Job Duties:
The Clinical Research Manager will be accountable for the following key responsibilities, including but not limited to:

Program Launch, Stakeholder Engagement & Strategic Oversight:

• Serve as the primary operational lead and central point of contact for internal and external stakeholders.
• Maintain strong, trust-based relationships with investigators, clinical teams, research operations, and external partners, without duplicating or micromanaging their operational functions.
• Establish structured communication, reporting, and escalation pathways to remain informed of study progress, risks, milestones, and resourcing needs while respecting existing operational ownership.
• Lead cross-program coordination to ensure alignment of scientific priorities, study timelines, regulatory strategy, and deliverables.
• Support study planning, feasibility assessment, and protocol development in partnership with investigators and operational leads embedded within the collaborating programs.

Team Building & Operational Expansion:

• Lead the recruitment, onboarding, training, and supervision of clinical research staff as the program grows.
• Build and manage a high-performing clinical research team, including workload planning, performance management, and professional development.
• Ensure compliance with ICH-GCP, institutional policies, and regulatory requirements across all studies.
• Implement continuous quality improvement initiatives and scalable infrastructure to support a growing and complex research portfolio.

• At minimum, a completion of a bachelor’s degree program, or recognized equivalent in Health or Science Related Discipline. 
• 3-5 years clinical and/or professional experience, and 2-3 years supervisory/management experience
• Possess leadership and managerial skills and have recognized experience in these areas
• Demonstrate relevant clinical research knowledge
• Excellent written and verbal communication skills, excellent organization, prioritization skills, good computer skills, ability to learn quickly and work independently
• Excellent interpersonal skills
• Ability to work under pressure and attention to detail
• Ability to perform duties in a professional and courteous manner and produce high quality work while meeting deadlines in accordance to UHN standards
• Ability to perform multiple concurrent tasks
• Knowledge of applicable legislative, UHN and/or departmental policies
• Client service oriented, with the ability to effectively work with diversity and appreciate that people with different opinions, backgrounds and characteristics bring richness to the challenge or situation at hand
• Certification as a Clinical Research Professional, preferred
• Work in compliance with UHN Vaccination Policy

Why join UHN?

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates.  Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.