About Synapticure
As a patient and caregiver-founded company, Synapticure provides instant access to expert neurologists, cutting-edge treatments and trials, and wraparound care coordination and behavioral health support in all 50 states through a virtual care platform. Partnering with providers and health plans, including CMS’ new GUIDE dementia care model, Synapticure is dedicated to transforming the lives of millions of individuals and their families living with neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS.
Synapticure conducts innovative, patient-centered research programs, including remote and decentralized clinical trials and Expanded Access Programs (EAPs), designed to bring investigational therapies to patients who need them most.
The Role
The Clinical Research Coordinator II (CRC II) plays a critical role in supporting Synapticure’s remote and decentralized research portfolio, including an Expanded Access Program providing investigational treatment for individuals living with ALS. This role is ideal for an experienced research professional who can manage study activities independently while partnering closely with investigators, research leadership, and cross-functional clinical teams.
As a CRC II, you will oversee day-to-day study execution, ensure regulatory and documentation compliance, and serve as a primary point of contact for research participants and caregivers. You will balance operational rigor with compassion, helping deliver a seamless, ethical, and patient-centered research experience in a fast-paced, mission-driven environment.
Successful candidates are detail-oriented, proactive, and comfortable navigating complex research workflows while supporting patients and families affected by neurodegenerative disease.
Job Duties – What you’ll be doing
Independently coordinate assigned study activities in compliance with protocols, SOPs, GCP, and regulatory requirements.
Screen and evaluate potential research participants for eligibility, documenting inclusion/exclusion criteria and escalating complex questions as needed.
Manage scheduling and execution of virtual and home-based study visits, assessments, and follow-up activities.
Collect, review, and enter study data accurately and in a timely manner using EDC systems and study tools.
Maintain complete, accurate, and audit-ready study documentation, including regulatory binders, participant records, and tracking logs.
Conduct or support informed consent discussions, ensuring proper documentation, version control, and regulatory compliance.
Serve as a primary point of contact for research participants and caregivers, addressing routine questions and coordinating logistics.
Prepare for and support sponsor, IRB, and regulatory monitoring visits, including responding to document requests and resolving findings.
Track and report study metrics such as enrollment, retention, deviations, and visit completion.
Identify operational risks or inefficiencies and proactively communicate improvement opportunities to research leadership.
Collaborate closely with investigators, care coordinators, and cross-functional teams to ensure a high-quality research experience.
Support onboarding and informal mentoring of junior research staff, as appropriate.
Requirements – What we look for in you
Bachelor’s degree in a scientific, health-related, or behavioral field preferred.
2–3 years of experience as a Clinical Research Coordinator or equivalent role.
Experience working with human subjects research required; neurology, ALS, or decentralized trial experience preferred.
Working knowledge of GCP, informed consent requirements, and clinical research regulations.
Ability to manage study responsibilities independently while knowing when to escalate issues.
Strong organizational skills with the ability to prioritize across multiple studies and deadlines.
Excellent written and verbal communication skills, including comfort working directly with patients and caregivers.
Experience using EDC systems, CTMS, electronic health records, and study tracking tools.
Comfort working in a fully remote research environment using virtual communication platforms.
Collaborative, adaptable, dependable, and aligned with Synapticure’s mission and values.
We’re founded by a patient and caregiver, and we’re a remote-first company. This means our values are at the heart of everything we do, and while we’re located all across the country, these principles are what tie us together around a common identity:
Relentless focus on patients and caregivers. We are determined to provide an exceptional experience for every patient we have the privilege to serve, and we put our patients first in everything we do.
Embody the spirit and humanity of those living with neurodegenerative disease. Inspired by our founders, families, and personal experiences, we recognize the seriousness of our patients’ circumstances and meet that challenge every day with empathy, compassion, kindness, and hope.
Seek to understand, and stay curious. We start by listening to one another, our partners, our patients, and their caregivers. We communicate with authenticity and humility, prioritizing honesty and directness while recognizing we always have something to learn.
Embrace the opportunity. We are energized by the importance of our mission and bias toward action.
