Company Overview:
Beam Therapeutics is committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform that includes a suite of gene editing and delivery technologies and is in the process of building internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of potential therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.
Position Overview:
The VP, Clinical Development will serve as the medical lead for base editing gene therapies in our hematology franchise and represent Beam both internally and externally. The candidate will develop the vision, mission, outline the strategies, establish the priorities, create alignment, and ultimately have full accountability for Beam’s hematology efforts. The VP of Clinical Development will oversee the strategy, implementation and maintenance of hematology internal clinical development programs and will also have the strategic view and execution strength to assist in business development, including growing the strength of the current internal pipeline and additional acquisitions. In addition, will be responsible for communicating the Beam Vision and Values in hematology to other functional groups and to external stakeholders.
Responsibilities
- Lead efforts to develop, refine a vision for the Beam hematology franchise strategy in a collaborative environment.
- Develop and implement near- and long-term goals and objectives that are aligned with the strategic vision.
- In line with corporate objectives, provide relevant medical counsel and scientific guidance to all teams across Beam that are involved in hematology therapeutic-related activities.
- Work with cross-functional teams to develop integrated clinical/regulatory strategies for key initiatives to support the successful registration and commercialization of products for the hematology therapeutic area.
- Support cross-functional hematology teams.
- Design clinical development plans, target-product profiles and protocols that are aligned to support the integrated clinical/regulatory/commercial strategies for the therapeutic area.
- Provide strategic and medical oversite of planned and ongoing clinical trials.
- Ensure high quality clinical development standards with respect to clinical study design, conduct and oversight of patient safety.
- Support the Research & Development Leadership Team as well as Business Development as it relates to hematology research and clinical development activities.
- Attend and help prepare material for medical conferences, Regulatory Agency meetings, Advisory Boards and other relevant clinical events as required.
- Mentor junior clinical research and development physicians and clinical scientists.
Qualifications
- MD, DO or equivalent ex-US medical degree with 15+ years’ experience, 10+ years clinical development experience in industry is a must. Final level and scope of role will be commensurate with experience.
- Board certification/eligibility in hematology, or equivalent is a must. Transplant experience is highly desirable.
- Must have previous patient care experience.
- Demonstrated ability to successfully execute clinical development projects across all phases of drug discovery.
- Proven track record of successful interactions with regulatory authorities.
- Demonstrated ability to lead and influence experienced professionals
- Experience working with commercial strategies in required
- Ability to lead in a fast-changing environment
- Broad knowledge and exposure across all R&D functions
- Deep understanding of pre-clinical/clinical pharmaceutical development
- Strategic thinker with strong execution skills
- Effective communicator
Location Requirement:
- This is a hybrid role however; this role requires that the candidate(s) live within a reasonable commuting distance to be on site in our Cambridge location several times per week.
