The Company
Dyno Therapeutics is reshaping the gene therapy landscape through AI-powered vectors. Through the application of our transformative technologies and strategic partnerships with leaders in gene therapy, we believe a future with life changing gene therapies for millions of people is within reach.
Our team includes world-class molecular and synthetic biologists, protein engineers and gene therapy scientists working alongside software engineers, data scientists, and machine learning experts to transform the landscape of available gene therapy capsids. Dyno has been named the 2021 NEVY Emerging Company of the Year, an Endpoints 11 Company and one of America’s Best Startups by Forbes in 2022 and 2023!
The Role
As a Sr. Scientist - AAV Capsid Engineering, you will lead and support experimental research staff in developing vector production capabilities within the CNS Design Team. You will be responsible for providing technical leadership, hands-on lab support, and guidance for junior team members while driving innovative capsid engineering methods for improved productivity in viral vector production.
How You Will Contribute
As a Sr. Scientist - AAV Capsid Engineering, you will directly influence Dyno’s ability to internalize and optimize vector production processes for CNS capsid development.
Responsibilities:
- Review experimental plans, provide hands-on support during vector production, and help junior researchers improve their experimental designs.
- Play a critical role bench-side during AAV vector production to increase team capacity and support decision making.
- Develop and optimize methods to improve capsid productivity.
- Contribute to the planning and strategy of both in vitro and in vivo studies to advance CNS capsid engineering.
- Manage and mentor a small team of Research Associates, guiding them through daily laboratory work and long-term career development. You will also be responsible for ensuring high performance by setting clear expectations, providing feedback, and fostering a collaborative team culture.
- Collaborate closely with computational scientists to integrate data from multiple sources. You will ensure your team’s efforts align with broader company goals and contribute to successful project outcomes.
- As a scientific leader, you’ll split your time between hands-on laboratory work and strategic oversight of your team’s activities. You’ll play a pivotal role in both executing experiments and ensuring the team meets project milestones, maintaining flexibility to step into different roles as needed.
Who you are
- Thoughtful and detail-oriented, able to balance leadership with hands-on responsibilities.
- Enthusiastic about CNS capsid design and its potential to meet patient needs.
- Passionate about AAV production and excited to collaborate on cutting edge capsid engineering innovations.
- Team player mentality with a passion for collaboration.
- Motivated by innovation at the intersection of data science and biology.
- Quantitative mindset with a focus on data-driven decision-making.
Basic qualifications
- PhD in biology, molecular biology, neuroscience, or equivalent experience.
- 2+ years of industry experience in biotech or pharma.
- Direct experience in AAV viral production.
- Strong foundation in molecular biology techniques (RNA/DNA methods, NGS, protein purification).
- Proven people management experience, including performance management responsibilities.
- Expertise in designing and planning experiments, with data interpretation skills.
Preferred qualifications
- Experience in pooled screening or AAV biology.
- Knowledge of high-throughput screening methods and data analytics.
Fraud Alert: Please be aware of recruitment scams targeting job seekers. Dyno Therapeutics will never make an offer of employment without conducting a formal interview process, nor will we ask for personal information such as financial details over email. Official communication will only come from an @dynotx.com email address. If you are contacted by someone claiming to represent Dyno Therapeutics from any other domain, please report it as spam and report the communication to us at [email protected].
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Job Type: Full-time
