10x Genomics is hiring a

Sr. Manager II, Mechanical Engineering

Position Summary:

We are seeking a dynamic and experienced Senior Manager II, Mechanical Engineering to lead and develop a high-performing team of engineers in the design, development, and commercialization of innovative biotech products. Based in our Singapore office, this role will require expertise in mechanical engineering, a proven track record of bringing products to market, and the ability to collaborate effectively with US-based teams. This position offers an exciting opportunity to mentor a growing team, and play a pivotal role in delivering cutting-edge solutions to the market.

Key Responsibilities:

  • Build, lead, and manage a team of mechanical engineers, driving technical excellence and fostering professional growth.
  • Establish team performance metrics and accountability structures to ensure on-time delivery of high-quality engineering solutions.
  • Act as a key stakeholder in global product development strategy, providing technical insights to guide decision-making.
  • Oversee the design, analysis, and development of complex mechanical systems, ensuring solutions meet product performance, cost, and manufacturability requirements.
  • Manage all stages of the product lifecycle, including conceptual design, prototyping, testing, validation, and transition to manufacturing.
  • Resolve high-impact technical challenges, drawing on deep mechanical engineering expertise and structured problem-solving techniques.
  • Ensure rigorous testing, validation, and documentation of mechanical systems to meet performance, safety, and quality standards.
  • Partner closely with US-based product development and operations teams to ensure successful delivery of products to market.
  • Navigate time zone differences and cultural dynamics to maintain productive working relationships with teams in the US and other global locations.
  • Leverage industry best practices and emerging technologies to maintain a competitive edge in product design and development.

Required Qualifications:

  • Bachelor’s degree in Mechanical Engineering or a related field (Master’s or Ph.D. preferred) with 15+ years of experience, including at least 7 years in a leadership or management role.
  • Proven track record of developing and commercializing complex mechanical systems and devices, particularly in biotech or related industries.
  • Demonstrated success in managing end-to-end product development, from concept through launch, with teams based in the US and globally.
  • Strong technical expertise in CAD (e.g., SolidWorks), FEA, thermal and fluid dynamics, and materials science.
  • Extensive experience in collaborating with global manufacturing teams to optimize designs for production and market readiness.
  • Strong knowledge of regulatory and quality requirements for product commercialization, including experience with PLM/QMS platforms (e.g., Arena).
  • Exceptional leadership and communication skills, with the ability to mentor team members and collaborate effectively across cultures and time zones.

Preferred Qualifications:

  • Experience working in a highly regulated industry (e.g., biotech, medical devices, life sciences).
  • Familiarity with US-based market dynamics, customer expectations, and supply chain considerations.
  • Demonstrated ability to influence cross-functional teams and senior leadership on critical technical and strategic decisions.

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. 

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

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