Sygnature Discovery Limited is hiring a

Senior Scientist (Translational Oncology)

Nether Alderley, United Kingdom
Full-Time
Background
Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma, biotech and NFP organisations.
Since 2004, Sygnature Discovery has delivered over 40 novel pre-clinical and 22 clinical compounds, with its scientists named on over 170 patents. Therapeutic areas of expertise include oncology, inflammation and immunology, neuroscience, metabolic diseases, infectious diseases, fibrotic diseases and more. To find out more, please visit www.sygnaturediscovery.com.  

About the role

Due to business growth, we are looking for a bright and experienced Senior Scientist to join our dynamic Translational Oncology Department at Alderley Park. As a Senior Scientist, you will play a crucial role in supporting all in vivo aspects of drug discovery projects using specialist oncology disease models.

You will plan, design, and execute projects whilst actively contributing to the discovery of new drugs across a broad range of projects and molecular targets, working with a wide variety of therapeutic modalities. In vivo experience in Oncology is essential.

This is a fantastic opportunity for someone looking to further develop and expand their scientific and technical expertise within a fast-growing, innovative drug discovery company.

Principal responsibilities will include:

  • Application of their scientific and technical knowledge of the use of oncology pharmacology models in drug discovery.
  • Provides strong technical oversight in their area of expertise.
  • Lab based role with significant non-lab-based roles and responsibilities.
  • Responsible for independent critical analysis and interpretation of own experimental data.
  • Co-ordination of the delivery of high-quality scientific data and interpretation to projects/clients.
  • Presents scientific findings, interpretations, and recommendations to the project/functional team, and/or clients with minimal guidance from the project leader.
  • Provides scientific guidance and/or mentoring to less experienced team members to ensure high quality science is delivered
  • May supervise more junior team members.

Key requirements:

  • Life Science PhD or equivalent
  • Track record in oncology drug discovery gained within the CRO, pharmaceutical or biotechnology sector.
  • Experience of the use of oncology in vivo models in drug discovery.
  • Experience in a range of ex-vivo analysis platforms.
  • Ability to interpret and problem solve complex data sets.
  • Excellent planning and organisational skills.
  • Ability to work flexibly and under pressure adapting to evolving project needs. 
  • Excellent team player with the ability to collaborate with internal and external cross functional teams.
  • Excellent written and verbal communication skills
  • An in-depth knowledge of ASPA 1986
  • High ethical and welfare standards
  • Keen eye for detail and concern for standards.
  • Ability to work independently and as part of a larger team as required.
  • Excellent record keeping skills.
  • Individual should be self-motivated and enthusiastic.

Why Sygnature Discovery
 
At Sygnature Discovery, we embody excellence in everything we do. From pioneering research to ground-breaking discoveries, we set the standard for scientific innovation. But it's collaboration that truly defines us. Across continents and disciplines, we unite to solve complex challenges, driven by a shared passion for improving lives worldwide.
 
We understand the importance of creating a work environment that empowers you to thrive. That’s why we have fostered a culture of collaboration and support, providing pathways for both professional and personal development. This includes a diverse range of bespoke training and development designed to accelerate both your personal and career growth.
 
We are committed to fostering diversity and inclusion throughout our organisation. We encourage applications from individuals of all backgrounds, ethnicity, gender identity, sexual orientation, disability, neurodiversity, age, family or parental status, beliefs, nationalities and religions. We strive to cultivate an inclusive environment where all our colleagues feel empowered to bring their true selves to work.
 
If you’re interested in joining a company that places people at the heart of its business, please submit your application as soon as possible as we will be interviewing on an ongoing basis.
 
If you have any questions or need further information, please contact the Talent Acquisition team at [email protected]. Please do not submit your application to this email address. 
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