Senior Research Associate, Mammalian Cell Culture

Company Summary

Flagship Labs 97 Inc. (FL97) is a privately held, early-stage technology company pioneering the application of artificial intelligence to transform every aspect of the scientific method. FL97 is backed by Flagship Pioneering, which brings the courage, long-term vision, and resources needed to realize unreasonable results. Join our mission-driven team and contribute to the future of science.

Our Life Sciences effort is leveraging AI and high-throughput automation for valuable therapeutic discovery and development across biological modalities.

At FL97, we are uniquely cross-functional and collaborative. We are actively reimagining the way teams work together and communicate. Therefore, we seek individuals with an inclusive mindset and a diversity of thought. Our teams thrive in unstructured and creative environments. All voices are heard because we know that experience comes in many forms, skills are transferable, and passion goes a long way.

If this sounds like an environment you’d love to work in, even if you only have some of the experience listed below, please apply.

The Role

FL97 is seeking a detail-oriented and experienced Research Associate with 2-5 years of hands-on experience in mammalian cell culture and high-throughput cell-based assays. The ideal candidate will demonstrate proficiency in sterile technique, automation systems, and cell line maintenance. We are looking for someone who is adept and independent at troubleshooting experimental workflows, optimizing culture conditions, and collaborating within cross-functional teams to support innovative therapeutic development.

Responsibilities Include:

• Build and support an operational cell culture process, including maintenance, proliferation and cryo banking. Collaborate with software team to create an end-to-end software solution for the cell culture operation system.
• Perform optimization efforts for mammalian cell culture protocols, increasing efficiency and reproducibility across experiments.
• Maintain accurate and thorough documentation of experimental protocols, data, and observations in electronic lab notebooks (ELNs).
• Assist in automation of workflows using liquid handling systems to streamline cell culture processes.
• Carry out transient and stable transfection protocols for protein expression, maintaining sterility and minimizing contamination risks.
• Develop and execute cell-based assays (e.g., viability, cytotoxicity, proliferation) to assess the impact of various experimental conditions.
• Collaborate in cross-functional teams, contributing insights to study design, process improvement, and project planning.

Qualifications:

• BS/ MS in Biology, Biotechnology or a related field.
• 2-5 years of experience in mammalian cell culture operations, including iPSC maintenance and differentiation.
• Experience with cell-based assay development, such as ELISA, fluorescence, luminescence, HTRF and AlphaLisa is desirable.
• Experience with Python programming is a plus.
• Excellent communication and collaboration skills.
• Quick learner with the ability to thrive in a fast-paced, innovative, and collaborative environment

Working at FL97, you would have access to advanced technology in the areas of:

• AI experimental design and simulation
• Automated instrumentation
• Generative molecular design

About Flagship

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.