Senior Research Associate/Associate Scientist, Assay Development

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?

Company Summary:
Quotient Therapeutics, Inc. is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.

Quotient Therapeutics, Inc. was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA) Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS). To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.

Position Summary:

We are seeking a high motivated Senior Research Associate or Associate Scientist to execute target validation experiments using in vitro model systems aimed to validate targets identified through our platforms. 

Responsibilities:

• Work under the supervision of senior members of the team and assist in designing and implementing research protocols.
• Perform laboratory experiments and apply various laboratory techniques including flow cytometry, ELISA, qPCR, Western blotting, and primary cell isolation and culture.
• Conduct in vitro and ex vivo assays, such as but not limit to overexpression, knockdown, knockout on primary cells, stimulation, and cytokine profile or functional assays.
• Collect, analyze and interpret scientific data accurately.
• Maintain precise experimental records and documentation.
• Contribute to the preparation of research articles, reports and presentations.
• Follow lab safety procedures and rules to ensure a safe working environment.
• Participate in regular team meetings to discuss progress, challenges, and future plans.

Qualifications:

• Bachelor's or Master’s degree in Immunology or related field.
• Minimum of 3 years of laboratory research experience.
• Familiarity with immunological assays such as ELISA, Flow Cytometry, and primary cell culture techniques.
• Previous experience with CRISPR and RNAseq.
• Previous experience with lentiviral transductions or AAV transfection/transduction is a plus.
• Good data organization, management, and analysis skills.
• Excellent oral and written communication skills.
• Ability to work effectively in a fast-paced, team-oriented environment.
• Attention to detail, ensuring robust and consistent experimental results.
• Prior experience in an industrial setting, and familiarity with Good Laboratory Practice (GLP) as well as proficiency in the use of Electronic Laboratory Notebooks (ELN). 

Location: Cambridge, MA