Who we are:
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X or LinkedIn.
How we work:
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PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
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COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
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BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.
How you’ll contribute:
- Contribute to the creation, design, and execution of Kymera’s clinical development strategy, collaborating with cross-functional teams (Biometrics, Regulatory, Clinical Operations) and external advisors.
- Provide scientific leadership in clinical trial design, protocol development, and data analysis for early- and late-stage assets, ensuring adherence to FDA, EMEA, ICH, and GCP guidelines.
- Serve as a member of the Clinical Study Team and Global Clinical Development SubTeam, participating in program meetings and safety monitoring reviews.
- Manage internal and external communication of project updates, regulatory submissions, publications, and presentations.
- Ensure patient safety by conducting clinical and medical data reviews, monitoring protocol adherence, and managing protocol deviations.
- Collaborate with Clinical Operations and Data Management to ensure data accuracy and integrity, identify risks, and propose mitigation strategies, while maintaining consistent clinical data review practices across studies.
- Stay current on disease biology, therapeutic practices, and drug mechanisms of action, providing insights into the competitive landscape and strategic development pathways.
- Contribute to the preparation of scientific materials for conferences, publications, and presentations.
Skills and experience you’ll bring:
- A Bachelor’s Degree is required, with an advanced degree in life sciences or healthcare (PhD, MD, PharmD, MSc) preferred. Significant experience in late-stage drug development is highly desirable.
- 10+ years of experience in clinical trial planning, startup, execution, reporting, and publishing within the biotech/pharma industry. Experience in immunology, inflammation, or related therapeutic areas is a plus.
- Demonstrated expertise in protocol development, study report and investigator brochure (IB) authoring, and preparing regulatory submissions.
- Thorough knowledge of relevant regulatory guidelines, including GCP, ICH, and FDA standards, as well as a strong understanding of Quality practices within GCP.
- Proven track record of successfully collaborating with medical monitors, development operations, and clinical investigators.
- Proficiency in clinical trial management systems (CTMS) and databases.
- Highly analytical and organized, with strong critical thinking skills and a history of innovative problem-solving.
- Experience managing multiple tasks and priorities, especially under tight deadlines, with a keen attention to detail.
- Ability to work independently, in multi-disciplinary teams, and with external partners, demonstrating strong interpersonal skills.
- Exceptional communication skills, both written and verbal, with the ability to convey complex information clearly to diverse audiences.
- Strong influencing abilities, with a history of resolving complex issues in creative and effective ways, and the capability to lead cross-functional teams.
This position is based in Watertown, MA, and offers a hybrid work model with a minimum of 3 days/week in the office.
Skills and experience not an exact match?:
Go ahead and submit your resume (and a cover letter, if you’d like!). If this role isn't right for you, we can keep you in mind for future opportunities.
Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.
