Scientist I, Lead Development

The Role: 

The Technology Development group at Life Edit discovers new genome editing systems and establishes new editing capabilities and optimizes them to support efforts developing curative gene editing therapies and gene edited cell therapies. We are looking for an enthusiastic, competent, and self-motivated Scientist with a strong background in mammalian cell culture and genome editing to help expand our technology development platforms and therapeutic capabilities.   

Here’s What You’ll Do: 

• Perform routine cell culture to maintain various cell lines and execute experiments 
• Evaluate Life Edit gene editing systems in mammalian cells to identify optimally engineered systems for further therapeutic discovery and development 
• Lead the formulation of new strategies to improve Life Edit’s genome editors and develop cell-based assays by which to evaluate them
• Analyze experimental data and present scientific results at team research meetings
• Collaborate closely with computational biology, gene editing and preclinical teams
• Maintain meticulous records of experimental methods, tool development and protocols
• Follow current literature in the field of gene therapy and genome editing and attend conferences

Requirements: 

• PhD with 0 - 3 years of applicable experience in Molecular Biology, Cell Biology, or a related field; research experience in genome editing highly preferred
• Experience in culturing, transfecting, and analyzing mammalian cells using cell-based assays (flow cytometry, cell proliferation, and viability assays)—prior experience with primary cell lines is a plus
• Experience with modern molecular biology techniques including DNA/RNA extraction, PCR, qPCR, Flow cytometry and ELISAs
• Prior experience with CRISPR systems and familiarity with NGS techniques is advantageous
• Demonstrated ability to work independently as well as collaboratively in a team-oriented environment
• Exceptional oral and written communication skills

We’re committed to finding the best ways to support our teams so they can do their best work. We take care of our employees, right from the start. 

Health & Wellness 

• Medical, vision, and dental insurance covered at 90%
• Low deductible, no co-insurance and no copays for mental health visits (for in-network care)
• Annual fitness reimbursement

• Employer paid for access to wellness apps and programs like Task Human

Financial 

• Competitive compensation
• 401(k) retirement plans with a 4% employer match and no vesting period
• Employer-paid life insurance and short- and long-term disability insurance
  • Employer-sponsored flexible spending accounts (FSA) and dependent care account (DCA) 
• Access to a 1-on-1 financial advisor
• Commuter reimbursement benefit
• Monthly cell phone stipend

Time Off & Flexibility 

• Unlimited paid time off, including vacation, sick leave, family leave, personal days, and bereavement
• 18 paid company holidays, plus an end-of-year holiday shut down
• 12 weeks of parental leave
• Federal Family and Medical Leave Act (FMLA) and Massachusetts Paid Family and Medical Leave (PFML), administered by Unum

Development Journey 

• Insights Discovery training for every employee to make the most of workplace relationships
• Ongoing professional development, including manager training
• Access to LinkedIn Learning, a self-guided online education platform