Research Associate I/II, LNP Production

The Company:

FL85 is a Flagship-backed, privately held biotechnology company on a mission to transform the current approach to information molecule therapeutics to unlock their full therapeutic potential. In recent years, we have begun to experience the power of information molecules in treating historically undruggable diseases and in designing therapies with unprecedented turnaround times. FL85’s platform integrates nanoparticle development with world-class informatics technologies and a novel pipeline of experimentation and discovery to drive a new generation of highly effective, therapeutically relevant information molecule therapies. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

"Flagship Pioneering has conceived of and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies."

Position Summary

FL85 is seeking a highly talented and motivated individual to develop and optimize lipid nanoparticle (LNP) formulations. The candidate will be a key contributor to the development of the FL85 platform by enabling the production of LNPs of varying chemistries with multiple nucleic acid cargos. The successful candidate will have a strong technical background in LNP formulation, as well as good communication and collaboration skills.

Key Responsibilities

• Design and optimize LNPs for a wide variety of LNP compositions and cargos
• Identify critical formulation parameters to provide robust and reproducible LNPs
• Support the production and characterization of LNPs to supply preclinical studies
• Collaborate with scientists across the organization to advance company objectives and understanding of LNP function
• Thoroughly document results in electronic lab notebooks and present findings to cross-functional teams

Qualifications

• BS/MS in life sciences or engineering, with 1-3 years of relevant experience
• Experience producing and characterizing nucleic acid LNPs is desired
• Familiarity with common LNP formulation and characterization techniques is desired
• A strong team player with the ability to work both independently and on cross-functional teams in a fast-paced, entrepreneurial environment
• Ability to identify scientific issues and devise solutions
• Passion for scientific consistency and reproducibility
• Excellent organizational and communication skills

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.