Research Associate I, Antibody Engineering

Programmable DNA, the software of Life, is finally here! Twist Bioscience is developing a disruptive Synthetic DNA technology that will change the world, enabling widespread health and sustainability. Synthetic biologists will use our products to engineer how organisms produce cures to diseases, make everyday chemicals by using the atmosphere as the carbon source, enable plants to make their own fertilizers, and to create in-vivo diagnostics that alert us when we are sick, and many more applications.

We are seeking an outstanding, innovative, and creative Research Associate to join our antibody discovery effort. This research associate will play multiple roles within the Biopharma group and will work within a team responsible for antibody discovery utilizing in vitro display technologies, e.g. phage display, ribosome display, and yeast display.

What You’ll Be Doing

• Perform phage display library panning for both soluble protein and cell membrane targets
• Execute kinetic studies of antibody-antigen interactions using surface plasmon resonance (SPR) instrumentation
• Assist with library construction using various molecular cloning skills like PCR, restriction digestion, ligation, DNA gel purification, and transformation
• Run DNA sequencing by NGS and prep samples for Sanger sequencing, summarize sequencing results and be able to design necessary sequencing primers
• Record experimental findings and present to supervisor, in group meetings, and other stakeholders
• Perform high throughput primary ELISA binding assays with the help of automation
• Work collaboratively under aggressive timelines
• Must be able to work as an individual contributor and as a team

What You’ll Bring to the Team

• Your educational background includes a B.S/B.A. in molecular biology, biochemistry, protein engineering, biological chemistry, or a related discipline with minimum 1-year related work experience
• Knowledge and experiences in molecular biology, protein engineering or antibody engineering methods and applications
• Excitement to learn new techniques and can work collaboratively with others
• You thrive in a dynamic, quickly changing environment where we work cross functionally as a team
• Excellent oral/written communication and interpersonal skills

Preferred Qualifications 

• B.S./B.A. with a minimum of 1-year experience in molecular biology, protein/antibody engineering or a related field
• Solid skills in molecular biology 
• Experience with Carterra SPR, Biacore SPR or Octet BLI instrumentation a plus
• Experience with phage, ribosome or yeast display is a plus, but not required

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.