mRNA Process Development Co-op

Company Overview: 

Beam Therapeutics is committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform that includes a suite of gene editing and delivery technologies and is in the process of building internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of potential therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases. 

Position Overview: 

Beam is seeking a highly motivated co-op student to join our mRNA Process Development (PD) team from January through June 2025. The individual will work on advancing our process characterization activities to map out optimal conditions for synthesis and purification of mRNA. They will be responsible for design, execution, and analysis of process development studies. This role will have the opportunity to work hands on developing chromatographic techniques, ultra-filtration steps, and enzymatic reactions. We are looking for an enthusiastic learner who enjoys problem solving and collaborative projects.  

Responsibilities: 

• Design and execute chromatography process development studies that includes screening of new materials and protocols. 
• Contribute to development of enzymatic IVT reactions and ultrafiltration steps. 
• Coordinate with analytical testing team for data collection and analyses. 
• Document, summarize and present studies and findings to internal audience at group meetings. 
• Document and manage all experimental planning and results in electronic lab notebook, including statistical analysis and troubleshooting where appropriate.  
• Adhere to all laboratory safety requirements and procedures, assist in maintaining general laboratory functionality, including maintenance of lab equipment and receiving of lab supplies. 

Qualifications: 

• Pursuing a BS or MS in biochemistry, chemistry, biochemical engineering, or related field of study with at least 1 year of relevant laboratory experience.  
• Must be a team player, comfortable working collaboratively and thriving in a fast-paced environment  
• Proficient in Excel, PowerPoint, Word, and data analysis. Knowledge of basic statistical modeling is a plus. 
• Experience maintaining a lab notebook and following written protocols.  
• Motivated to learn and detail oriented with excellent organizational and communication skills.