Liver Co-op

Company Overview

Beam Therapeutics is committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform that includes a suite of gene editing and delivery technologies and is in the process of building internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of potential therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.

Position Overview:

Beam is seeking a passionate and motivated co-op student to join our expanding liver team from January through June 2025. The co-op will aid in advancing an early-stage liver program from discovery toward the clinic in a highly collaborative and fast-paced environment. The individual will be responsible for developing protein-based and biochemical assays for functional validation of base editing in vitro/in vivo to support liver drug discovery programs at Beam.

Responsibilities:

• Mammalian cell culture (immortalized/primary cells) and non-viral transfection.
• Perform molecular biology tasks, including DNA/RNA isolation, qPCRs, Next Generation Sequencing Prep, and protein assay development.  
• Maintain detailed documentation and effectively collaborate and communicate across a multidisciplinary team.

Qualifications:

• Pursuing a BS or MS in a biological science-related field with 1-2 years of hands-on laboratory experience.
• Knowledge of gene editing (CRISPR and/or base editing) is plus but not required.
• Experience with mammalian cell culture and basic molecular methods are desired.
• Proficiency in Prism, Excel, PowerPoint, and Electronic Lab Book programs is preferred.   
• Excellent troubleshooting, communication skills and the ability to work effectively in a team.