Director, Functional Genomics

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way?

About Vesalius

Vesalius Therapeutics is pioneering a revolutionary platform to generate breakthrough treatments for common diseases.  Vesalius’ platform uses large-scale human genetics, genomics, stem cell studies and artificial intelligence to uncover causal biology and identify optimal intervention points for new therapies. Efficiently identifying these intervention points and the patients most likely to benefit from these novel therapies will enable smaller, shorter clinical trials with a higher probability of success. Vesalius was founded in 2019 by Flagship Pioneering. For more information visit vesaliustx.com, or follow us on X and LinkedIn.

About the Position

Vesalius Therapeutics is seeking a highly motivated and collaborative Director of Functional Genomics to lead in the discovery of new therapeutic targets and the development of world-class target discovery platforms, such as CRISPR screening and high-throughput protein interaction assays platform. This individual will be responsible for assembling and leading a team with expertise spanning molecular biology, cell biology, cell engineering, assay development, and new technology development.  

Responsibilities 

• Design, develop and implement medium and high throughput functional genomic screens in cell lines, primary cells, and reprogrammed stem cell cultures. This includes deploying genome engineering and single-cell genomic technologies.  
• Evaluate and introduce new genome-scale technologies to the company, and champion their use in our discovery efforts  
• Be a strong voice in the development and implementation of our target discovery platform  
• Assemble and lead a team of skilled scientists to execute this mission, and collaborate across our diverse group of scientific disciplines to develop new ideas  

Qualifications  

• PhD in a biological discipline with at least 8-10 years of relevant experience in an industry or academic setting. Additional qualifications, including MD, strongly preferred.  
• An outstanding reputation in your field as a creative scientist, a technology innovator, and as a dynamic leader, evidenced by publication track record and/or patent filings.  
• Deep expertise in cell and molecular biology and experience with state-of-the-art functional genomics screening technologies including contemporary expertise with CRISPR technologies used for genome-wide screens  
• Extensive experience with cell-based assay development and screening using a variety of readout technologies.  
• Strong quantitative intuition, excellent data analysis and data mining skills, and experience and comfort with laboratory automation.  
• Direct supervisory experience (5+ years) leading a team of scientists (including PhD-level scientists) and a track record of recruiting, mentoring, and developing top talent.  
• Outstanding communication, collaboration, networking, and program leadership skills.  
• Demonstrated ability to work in a dynamic environment with a sense of urgency and creativity and focus on deliverables.
• Team player with a strong work ethic, able to work both independently and collaboratively 
• Continuously learns and adapts quickly to new information
• Authentic, proactively appreciative of different points of view, backgrounds and perspectives

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Vesalius is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. 

At Vesalius, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Vesalius Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Vesalius or its employees is strictly prohibited unless contacted directly by the Vesalius internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Vesalius, and Vesalius will not owe any referral or other fees with respect thereto.