Who We Are
Cogent Biosciences is a publicly traded biotechnology company developing real solutions to treat genetically driven diseases. With a focus on rational drug discovery and development, we are leveraging validated biology to advance precision therapies designed to address the true underlying drivers of disease and provide real hope for patients. Cogent’s lead therapeutic candidate, bezuclastinib (CGT9486), is a precision kinase inhibitor designed to selectively and potently inhibit the KIT D816V mutation. This mutation is responsible for driving a rare and serious condition called Systemic Mastocytosis (SM), which can severely impact many different tissues and organs in the body. We are also studying CGT9486 to treat advanced gastrointestinal stromal tumors (GIST), which have a strong dependence on oncogenic KIT signaling. We are currently enrolling two Phase 2 clinical trials for patients with SM and a global Phase 3 trial for GIST patients.
Our Team
https://cogent.culturehq.com
This role will assist in the development and implementation of Cogent’s overall commercial supply chain strategy for it’s first anticipated product to market.
Responsibilities:
- Responsible for vendor(s) selection and oversight for commercial supply chain
- Lead RFP planning including drafting business requirements for the selection of a Contract Packaging Organization (CPO). Oversee the commercial packaging qualification process at the CPO to ensure processes, operations, systems, and equipment are validated.
- Lead RFP planning for the selection of a Level 4 Serialization Vendor. Develop serialization labeling and EPCIS user requirements to be used in the evaluation and selection of an EPCIS system. Oversee the implementation and validation of the system.
- Implement and manage processes for artwork and serialization to ensure compliance and product traceability.
- Work with the commercial team on the evaluation and selection of a Third-Party Logistics Provider. Collaborate with commercial team to align supply chain activities with market demands.
- Lead planning activities to ensure accurate and timely availability of product. Develop and manage supply plans in coordination with production schedules and sales forecasts. Identify potential risks within the supply chain and develop mitigation strategies to ensure business continuity.
- Oversee end-to-end supply chain operations, including production, inventory management and distribution. Manage GMP inventory throughout the supply chain, manage upcoming expiry, and ensure drug product accountability.
- Establish and maintain strategic relationships with suppliers to ensure reliability, quality, and cost-effectiveness. Manage supplier performance, and mitigate risks associated with supply disruptions. Serve as a central point of contact for commercial supply chain-related issues and initiatives, ensuring alignment and coordination among all stakeholders.
- Develop key supply chain metrics and Key Performance Indicators (KPI) reports to be presented to senior management and stakeholders and support the creation of the Sales and Operations Planning (S&OP) processes.
- Drive continuous improvement in supply planning processes and systems, including the implementation of new technologies and tools.
- Assist in the creation of Standard Operating Procedures
- Collaboratively work across the organization with cross functional stakeholders
Requirements:
- Bachelor’s degree and minimum of 15 years of experience in the pharmaceutical industry
- Experience in transitioning supply chain functions from clinical stage to commercial launch in a biopharmaceutical company is strongly preferred.
- Strong knowledge of supply chain principles, including demand planning, procurement, logistics, and inventory management.
- Experience with supplier and vendor management, contract negotiation, and performance monitoring.
- Familiarity with regulatory requirements and quality standards in the pharmaceutical industry.
- Excellent analytical, problem-solving, and decision-making skills.
- Strong communication and interpersonal skills
- Ability to collaborate effectively across functions and with external vendors. Commitment to continuous improvement and innovation.
- Able to work in a fast pace, dynamic environment
- Solid oral dosage experience is preferred
Our Locations
Waltham, MA: Our Boston office includes an open office layout that has recently undergone a makeover designed for collaboration and giving our employees the best work place possible. Free access is provided for both on-site parking and gym facilities in the building.
Boulder, CO: We have just moved into our new state-of-the art Research Facility in the fast-growing biopharmaceutical hub in the greater Denver/Boulder corridor. Our CEO is based full-time in this location and we are proud to call this the home of Cogent’s discovery research organization.
Our Offer To You
To attract the very best talent, we offer a generous benefits package that includes competitive pay, performance-based bonus, stock options, insurance coverage (health, dental, life, and disability), competitive time-off, a 401(k) plan, and commuter/parking benefits.
We are proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability, or any other status protected under federal, state, or local law. All employment is decided on the basis of qualifications, merit, and business need.
