Background
Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma, biotech and NFP organisations.
Since 2004, Sygnature Discovery has delivered over 40 novel pre-clinical and 22 clinical compounds, with its scientists named on over 170 patents. Therapeutic areas of expertise include oncology, inflammation and immunology, neuroscience, metabolic diseases, infectious diseases, fibrotic diseases and more. To find out more, please visit
www.sygnaturediscovery.com.
The Protein Science department provides research services to clients globally. These services include the engineering of tailored proteins for a variety of different end-uses such as biochemical screening, biophysics, diagnostics, and biologics drug discovery. In addition, we perform protein structure determination by X-ray, cryo-EM and provide a protein mass spectrometry service. Our passion is to provide clients with the protein related tools and information they need to successfully progress their projects.
About the role
We are looking for a cell scientist to be part of our team involved in the generation of recombinant proteins for use in the pharmaceutical industry globally.
Essential to almost all the work we undertake is the ability to express proteins in a number of different cell hosts which include transient mammalian systems, baculovirus/insect cells and E.coli. The nature of the work is that you must have good attention to detail, you must be able to be very flexible and adaptable to an ever-changing environment of different approaches with different cell lines at different scales for different projects.
Role Responsibilities:
- This position will primarily involve expression of proteins in a variety of host cells.
- Within this role you will develop your experience and independence with core scientific skills that are relevant for protein expression activities.
- You will design and execute experiments with supervision initially, and then independently, but under relevant instruction to meet approved timelines and objectives.
- You will develop your skills to critically analyse, interpret and communicate the outcome of experiments in a timely manner to the project leader and/or team.
- You will plan your personal work and scheduling, including checking availability and ordering of equipment and consumables with help initially, but then independently.
- Where possible, you will gain client interaction exposure with support and under the supervision of senior team members.
- You will support the smooth running of the laboratory by keeping personal and communal lab areas clean and tidy and taking part in house-keeping activities, as directed by the lab manager/operations team.
- You may gain experience with basic informatics tools and ensures up-to-date ELN recordkeeping according to the Departmental guidelines. You may use software appropriate to the role, with necessary training as required.
- Use relevant lab equipment correctly and safely, with help from the appropriate Superuser, as and when required.
- Adheres to all SOPs, approved protocols, and guidelines.
Candidate Requirements:
- A degree in a biological science is essential at either BSc, MSc, or PhD level.
- Ideally, you will have cell culture experience and will have worked with at least one protein expression system and be able to use it at different scales and complexity to adapt to rapidly changing demands.
- You must have enthusiasm for lab work, demonstrating care and attention to detail when planning and performing experiments and be able to critically analyse your data to provide creative solutions to problems when they arise.
- The ability to work independently, but also flexibility as part of the team to ensure we meet customer needs.
Benefits
Here at Sygnature Discovery, we take pride in offering an excellent training and benefits package. As a valued employee, you will be entitled to:
- 25 days annual leave (rising with service) plus bank holidays, and buy/sell scheme
- Private Medical Insurance
- Life Insurance
- Employee Assistance Programme and mental health first aiders
- Enhanced Family Friendly Policies
- Sygnature Group Pension Scheme
- 1 paid volunteer day per year
- A host of flexible benefits to support your wellbeing and lifestyle
Why Sygnature Discovery
At Sygnature Discovery, we embody excellence in everything we do. From pioneering research to ground-breaking discoveries, we set the standard for scientific innovation. But it's collaboration that truly defines us. Across continents and disciplines, we unite to solve complex challenges, driven by a shared passion for improving lives worldwide.
We understand the importance of creating a work environment that empowers you to thrive. That’s why we have fostered a culture of collaboration and support, providing pathways for both professional and personal development. This includes a diverse range of bespoke training and development designed to accelerate both your personal and career growth.
We are committed to fostering diversity and inclusion throughout our organisation. We encourage applications from individuals of all backgrounds, ethnicity, gender identity, sexual orientation, disability, neurodiversity, age, family or parental status, beliefs, nationalities and religions. We strive to cultivate an inclusive environment where all our colleagues feel empowered to bring their true selves to work.
If you’re interested in joining a company that places people at the heart of its business, please submit your application as soon as possible as we will be interviewing on an ongoing basis.
If you have any questions or need further information, please contact the Talent Acquisition team at [email protected]. Please do not submit your application to this email address.
