Ocular Therapeutix, Inc. (NASDAQ:OCUL) is a biopharmaceutical company focused on the formulation, development, and commercialization of innovative therapies for diseases and conditions of the eye using its proprietary bioresorbable hydrogel-based formulation technology, ELUTYX™. Ocular Therapeutix has built a robust product pipeline of drug delivery solutions developed to reduce the complexity and burden of the current standard of care and position itself to become a leader in the ophthalmic space.
Outside of the ophthalmic realm and behind the doors of our headquarters in Bedford, MA, we strive to build a strong culture where employees can flourish and achieve their career goals. We encourage out of the box thinking, cross-functional collaboration, and creativity.
ANALYTICAL CHEMIST II
Position Summary:
Ocular Therapeutix is seeking an analytical chemist to support Pharmaceutical Development activities. This role will be responsible for laboratory testing to chemically and physically characterize the company’s lead sustained release hydrogel-based intravitreal implant drug product in support of commercial scale-up activities.
Principal Duties and Responsibilities include the following:
- Support Pharmaceutical Development activities to characterize the chemical and physical properties of implant prototypes generated during implant production scale-up studies.
- Perform analytical chemistry testing and data analysis using standard laboratory techniques and instrumentation (assay, purity, solubility, stability, dissolution).
- Support method development and testing internally and interface with contract analytical testing labs.
- Implement appropriate characterization methods to understand and anticipate drug product, API, and polymer-related physicochemical properties.
- Design and support implant scale-up studies for drug products, APIs, and polymers.
- Analyze, summarize, and present data to group and cross-functional project teams.
- Collaborate with a multidisciplinary team of chemists, engineers, and scientists to gather knowledge, identify gaps, design relevant experiments, transfer methods, and document information at appropriate project intervals.
- Support calibration and maintenance of analytical equipment as necessary.
- Follow good documentation practices (maintaining contemporaneous records, laboratory notebooks, equipment logbooks, forms, etc.).
Qualification Requirements:
- Degree in Chemistry, Pharmaceutics, Biochemistry, or related scientific discipline. MS or BS with 2+ years of relevant drug product analytical development experience desired.
- Prior analytical chemistry working experience in either quality or R&D groups in the pharmaceutical and/or biotechnology industry.
- Experience with HPLC/UPLC, GPC, LC-MS, Empower software. Experience with additional characterization techniques is a plus (UV-Vis, DSC, TGA, DVS, SEM/EDS, FT-IR, XRPD).
- Experience with polymer characterization is ideal.
- Excellent problem-solving, organizational, and communication skills.
- Experience and knowledge in analytical and bioanalytical chemistry, including common practices and techniques.
- Knowledge of safe laboratory practices.
- An understanding of GXP analytical operations and ICH/FDA guidelines is a plus.
- A collaborative, hard-working, team player passionate about science who can effectively work in a dynamic, cross-functional team environment.
Ocular Therapeutix is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws regarding nondiscrimination. Ocular Therapeutix provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, or status as a veteran. For information on how Ocular Therapeutix collects, stores, and utilizes candidate information please see our privacy policy found at https://www.ocutx.com/privacy-policy/.
